Description | APC anti-human CD4. CD4, also known as T4, is a 55 kD single-chain type I transmembrane glycoprotein expressed on most thymocytes, a subset of T cells, and monocytes/macrophages. CD4, a member of the Ig superfamily, recognizes antigens associated with MHC class II molecules and participates in cell-cell interactions, thymic differentiation, and signal transduction. CD4 acts as a primary receptor for HIV, binding to HIV gp120. CD4 has also been shown to interact with IL-16. |
Product Specific References | PubMed: 16849481, 24574397, 22028652, 23770626, 25024379, 25114162, 26700184, 26976045, 27482100, 27579340, 27641646, 27641646, 27840851, 28366645, 28928458, 29961579, 31069153, 31080066, 29752829, 31150624, 31080066, 29961579, 28878119, 31449552, 32248243, 32431798, 31636416, 32636834, 29227470, 33457103, 33628210, 33571449, 33811831, 34077752 |