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Antigenic Specificity | Human T-bet |
Clone | QA18A24 |
Host Species | Recombinant Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | PerCP-Cyanine5.5 conjugate |
Size | 25 tests |
Concentration | n/a |
Applications | Intracellular Staining for Flow Cytometry (ICFC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PerCP/Cyanine5.5 anti-human T-bet Recombinant. T-bet, also known as T-box transcription factor T-bet, is considered to be a "master regulator" of Th1 lymphoid development controlling the production of the cytokine IFN-γ. T-bet is widely expressed in hematopoietic cells including stem cells, NK cells, B cells, and T cells. T-bet is critical for the control of microbial pathogens, and knockout animals show multiple physiologic and inflammatory features characteristic of asthma. T-bet expression is optimally observed after IL-12 stimulation and can be suppressed by addition of the Th2 cytokine IL-4 or neutralization of IL-12. |
Immunogen | n/a |
Other Names | T-box expressed in T cells, T box 21, TBLYM |
Gene, Accession # | Gene ID: 30009 |
Catalog # | 365907 |
Price | $185 |
Order / More Info | Human T-bet Antibody from BIOLEGEND |
Product Specific References | n/a |