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Antigenic Specificity | Human Siglec-9 |
Clone | K8 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | TotalSeq™-C oligomer conjugate |
Size | 10 µg |
Concentration | n/a |
Applications | PG |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TotalSeq™-C1280 anti-human Siglec-9. Siglecs are cell surface receptors belonging to the immunoglobulin superfamily that recognize sugar antigens. The extracellular domain of siglec-9 contains an IgV region, which binds sialic acid, followed by two IgC regions. Siglec 9 and siglec 6-8,10-12 are CD33 (siglec 3) like siglecs, which have two ITIMs in the cytoplasmic tails, suggesting their functional involvement in signal transduction. It is highly expressed on neutrophils and monocytes, and at lower levels on the subpopulations of T and B lymphocytes and NK cells. Siglec-9 plays a role in negative regulation of T cell activation, and it also affects neutrophil apoptosis. |
Immunogen | Recombinant Siglec-9 fused to Fc region of human IgG |
Other Names | Sialic acid-binding Ig-like lectin-9, CD329 |
Gene, Accession # | Gene ID: 27180 |
Catalog # | 351525 |
Price | $369 |
Order / More Info | Human Siglec-9 Antibody from BIOLEGEND |
Product Specific References | n/a |