Edit |   |
---|---|
Antigenic Specificity | CD49C (Integrin α3) |
Clone | P1B5 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | unconjugated |
Size | 100 µL |
Concentration | n/a |
Applications | IHC-F, Flow Cytometry (FC), IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-CD49C (Integrin α3). CD49c is a 150 kD α integrin chain known as α3 integrin or VLA-3 α chain. It is a type I transmembrane glycoprotein which is proteolytically cleaved into two disulfide linked fragments of 125 kD and 30 kD. CD49c forms a heterodimer with integrin β1 (α3β1, CD49c/CD29, VLA-3) and is expressed by many types of adhesion cells, such as endothelial cells, epithelial cells, and dermal fibroblasts. Weak expression has been reported on leukocytes. VLA-3 plays a role in cell-cell and cell-matrix adhesion |
Immunogen | The P1B5 monoclonal antibody was generated against human HT1080 cells. |
Other Names | GAP-B3, GAPB3, ILNEB, MSK18, VCA-2, VL3A, VLA3a, FRP-2, galactoprotein B3, VLA-3 subunit alpha, CD49 antigen-like family member C, antigen identified by monoclonal antibody J143, very late activation protein 3 receptor, alpha-3 subunit |
Gene, Accession # | Gene ID: 3675 |
Catalog # | 921601 |
Price | $256 |
Order / More Info | CD49C (Integrin α3) Antibody from BIOLEGEND |
Product Specific References | n/a |