Description | APC/Cyanine7 anti-mouse CD86. CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activatio |
Product Specific References | PubMed: 25505280, 26115685, 22710245, 27068235, 27741278, 29463472, 30170810, 30811982, 30811982, 30170810, 28709002, 32439945, 30339853, 32183951, 31875551, 32375064, 31753725, 31216480, 32849581, 34019807 |