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Antigenic Specificity | Human IL-18 |
Clone | W17071A |
Host Species | Rat |
Reactive Species | human |
Isotype | IgG2a, κ |
Format | purified, low endotoxin, azide-free |
Size | 1 mg |
Concentration | n/a |
Applications | Neut |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Ultra-LEAF™ Purified anti-human IL-18. IL-18 was first identified as IFN-β-inducing factor (IGIF). It is a member of the IL-1 family of cytokines and similar to IL-1β, IL-18 is initially synthesized as an inactive precursor without a signal peptide and is cleaved into the mature form by activated caspase 1. Caspase 1-independent maturation of IL-18 is induced by FASL. Mature IL-18 binds directly to the IL-18 receptor alpha chain and then recruits IL-18 receptor beta chain to form a high affinity complex. The high affinity complex rec |
Immunogen | Recombinant human IL-18 |
Other Names | Interferon-gamma-inducing factor, IGIF, IL-1g, IL18, IL1F4 |
Gene, Accession # | Gene ID: 3606 |
Catalog # | 949704 |
Price | $1205 |
Order / More Info | Human IL-18 Antibody from BIOLEGEND |
Product Specific References | n/a |