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Antigenic Specificity | Tau Phospho (Thr231) |
Clone | PHF-6 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | purified, azide-free |
Size | 100 µL |
Concentration | n/a |
Applications | Western Blot (WB), IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified (azide-free) anti-Tau Phospho (Thr231). Paired helical filaments (PHFs) are the major building blocks of neurofibrillary lesions in Alzheimer?s disease brains and are composed of hyperphosphorylated tau protein. Predominantly expressed in axons, alternatively spliced forms of tau comprise a family of microtubule-associated proteins that normally promote and stabilize the assembly of microtubules. PHF-tau differs from normal tau by its abnormal hyperphosphorylation, which results in decreased binding of tau to microtubules. The decreas |
Immunogen | The PHF-6 antibody was raised using PHF-tau preparations from human brain. |
Other Names | Microtubule-associated protein tau, PHF-tau, paired helical filament-tau, neurofibrillary tangle protein, microtubule-associated protein tau, isoform 4, G protein beta1/gamma2 subunit-interacting factor 1 |
Gene, Accession # | Gene ID: 4137 |
Catalog # | 828901 |
Price | $357 |
Order / More Info | Tau Phospho (Thr231) Antibody from BIOLEGEND |
Product Specific References | PubMed: 25914109 |