Edit |   |
---|---|
Antigenic Specificity | RING1 |
Clone | P88C12F4 |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-RING1. RING1 is an E3 ligase that is essential for development in higher eukaryotes and plants. It is a critical component of the Polycomb-group (PcG) multiprotein PRC1-like complex, which acts to transcriptionally repress genes through post- translational modifications that block the assembly of the transcriptional pre-initiation complex. As a component of PRC1, RING1 plays a pivotal role in monoubiquitination of Histone H2A at Lysine 119, which is linked to transcriptional repression of Hox family me |
Immunogen | Partial recombinant human RING1 protein |
Other Names | RING1A, RNF1, Ring Finger Protein 1, E3 Ubiquitin Ligase RING1, EC:2.3.2.27, Really Interesting New Gene 1 Protein, RNF1 |
Gene, Accession # | Gene ID: 6015 |
Catalog # | 936702 |
Price | $253 |
Order / More Info | RING1 Antibody from BIOLEGEND |
Product Specific References | n/a |