Description | APC anti-human CD4. CD4, also known as T4, is a 55 kD single-chain type I transmembrane glycoprotein expressed on most thymocytes, a subset of T cells, and monocytes/macrophages. CD4, a member of the Ig superfamily, recognizes antigens associated with MHC class II molecules, and participates in cell-cell interactions, thymic differentiation, and signal transduction. CD4 acts as a primary receptor for HIV, binding to HIV gp120. CD4 has also been shown to interact with IL-16. |
Product Specific References | PubMed: 20668220, 23577054, 25148371, 27068708, 27207542, 28040323, 29967419, 29799520, 29632724, 29324226, 28778586, 31142603, 31380412, 31027998, 30917314, 29324226, 28778586, 27758159, 29780387, 30271775, 30796203, 31209354, 31836828, 31276594, 28475648, 28346410, 31178118, 33377097, 33103593, 32958743, 31959990 |