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Antigenic Specificity | Human CD163 |
Clone | QA19A16 |
Host Species | Recombinant Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | TotalSeq™-B oligomer conjugate |
Size | 10 µg |
Concentration | n/a |
Applications | SB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TotalSeq™-Bn1307 anti-human CD163 Recombinant. CD163 is a member of the group B scavenger receptor cysteine-rich superfamily, also known as GHI/61, M130, RM3/1, p155, hemoglobin-haptoglobin complex receptor, or macrophage-associated antigen. It is a 134 kD (non-reduced)/155 kD (reduced) glycoprotein primarily expressed on macrophages, Kupffer cells, monocytes, a subset of dendritic cells, and a subset of hematopoietic stem/progenitor cells. CD163 binds to haptoglobin-hemoglobin complex and TWEAK, and plays a role in clearing hemoglobin and regulating cytokine production by macrophages. Membrane CD163 can be cleaved by metalloproteinases (MMP), resulting in a soluble form. Elevated serum level of sCD163 has been implicated in many kinds of inflammatory diseases. |
Immunogen | n/a |
Other Names | GHI/61, M130, RM3/1, p155, Hemoglobin/Haptoglobin Complex Receptor, macrophage-associated antigen, ED2(rat) |
Gene, Accession # | Gene ID: 9332 |
Catalog # | 364307 |
Price | $369 |
Order / More Info | Human CD163 Antibody from BIOLEGEND |
Product Specific References | n/a |