Edit |   |
---|---|
Antigenic Specificity | β-Amyloid, x-42 |
Clone | 1-11-3 |
Host Species | Rabbit |
Reactive Species | human |
Isotype | IgG |
Format | purified, azide-free |
Size | 50 µg |
Concentration | n/a |
Applications | IHC-P, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified (azide-free) anti-β-Amyloid, x-42. Alzheimer's disease is characterized by the accumulation of aggregated Aβ peptides in senile plaques and vascular deposits. Aβ peptides are derived from amyloid precursor protein (APP) through sequential proteolytic cleavage of APP by β- and γ-secretases generating diverse Aβ species. Aβ can aggregate to form soluble oligomeric species and insoluble fibrillar or amorphous assemblies. Some forms of the aggregated peptides are toxic to neurons. |
Immunogen | n/a |
Other Names | Amyloid beta A4 protein, preA4, protease nexin-II, peptidase nexin-II, beta-amyloid peptide, alzheimer disease amyloid protein, cerebral vascular amyloid peptide, APP, Amyloid Precursor Protein |
Gene, Accession # | Gene ID: 351 |
Catalog # | 812101 |
Price | $431 |
Order / More Info | β-Amyloid, x-42 Antibody from BIOLEGEND |
Product Specific References | PubMed: 22938075, 18700006 |