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Antigenic Specificity | Human IL-17A |
Clone | BL168 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | purified |
Size | 500 µg |
Concentration | n/a |
Applications | Intracellular Staining for Flow Cytometry (ICFC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-human IL-17A. IL-17A is the founding member of the IL-17 family, a group of six structurally related pro-inflammatory cytokines. IL-17A, secreted by activated CD4 Th17 cell subpopulation, elicits multiple biological activities on a variety of cells including: the induction of IL-6, IL-8, G-CSF, and PGE2 production in epithelial, endothelial or fibroblasts; the enhancement of surface expression of ICAM-1 in fibroblasts; activation of NF-κB and costimulation of T cell proliferation. Recent studies demonstrated |
Immunogen | Recombinant full length human IL-17A |
Other Names | Interleukin IL-17A, IL-17, Cytotoxic T lymphocyte-associated antigen 8 (CTLA-8) |
Gene, Accession # | Gene ID: 3605 |
Catalog # | 512302 |
Price | $258 |
Order / More Info | Human IL-17A Antibody from BIOLEGEND |
Product Specific References | PubMed: 29058101, 29031634, 31533030, 28296284, 28337205, 31844089, 28103916, 29298833, 34077752, 34174183 |