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Antigenic Specificity | Human CD120b |
Clone | 3G7A02 |
Host Species | Rat |
Reactive Species | human |
Isotype | IgG2a, κ |
Format | purified, low endotoxin, azide-free |
Size | 500 µg |
Concentration | n/a |
Applications | Neut, Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Ultra-LEAF™ Purified anti-human CD120b. CD120b, also known as TNFRII or TNFRSF1B, belongs to the TNF receptor superfamily and can interact with ligands TNF-α and TNF-β (also known as LT-α). It is a 75 kD type I transmembrane protein expressed on lymphocytes, monocytes, and granulocytes. When present in a heterocomplex with CD120a, it induces the recruitment of anti-apoptotic molecules, c-IAP1 and c-IAP2 that possess E3 ubiquitin ligase activity. Mutations in CD120b are associated with TNF-associated periodic syndrome (TRAPS) or period |
Immunogen | Partial CD120b recombinant protein expressed in 293E cells (22-211aa). |
Other Names | TNFRSF1B, p75, p75TNFR, TNFR2, TNFR80, TBPII |
Gene, Accession # | Gene ID: 7133 |
Catalog # | 358408 |
Price | $385 |
Order / More Info | Human CD120b Antibody from BIOLEGEND |
Product Specific References | PubMed: 31875557, 33490159, 33490159 |