Human CD221 (IGF-1R) Antibody from BIOLEGEND
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| Antigenic Specificity | Human CD221 (IGF-1R) |
| Clone | 1H7/CD221 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1, κ |
| Format | phycoerythrin (PE) conjugate |
| Size | 100 tests |
| Concentration | n/a |
| Applications | Flow Cytometry (FC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | PE anti-human CD221 (IGF-1R). CD221, also known as insulin-like growth factor 1 receptor (IGF1R), is a 135 kD transmembrane receptor. It is widely expressed on lymphoid and myeloid cells as well as non-haematopoietic cells. CD221 is a tyrosine kinase receptor and the ligands for CD221 are insulin-like growth factor 1 and 2 (IGF-1 and IGF-2), the polypeptide hormones similar in molecular structure to insulin. IGF-1/2 binding activates downstream PI3K and MAPK pathways and plays an important role in cell growth. Recent studies |
| Immunogen | IGF-1 receptor purified from human placentas |
| Other Names | Insulin-like growth factor 1 receptor (IGF1R) |
| Gene, Accession # | Gene ID: 3480 |
| Catalog # | 351806 |
| Price | $304 |
| Order / More Info | Human CD221 (IGF-1R) Antibody from BIOLEGEND |
| Product Specific References | PubMed: 25349219 |
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