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Antigenic Specificity | Human FOXP3 Delta 2 (exon 2 deleted) |
Clone | A15080A |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-human FOXP3 Delta 2 (exon 2 deleted). FOXP3 is a transcription factor which is proposed to be a master regulatory gene and more specific marker of T regulatory cells than most cell surface markers (such as CD4 and CD25). Transduced expression of FOXP3 in CD4 /CD25- cells has been shown to induce GITR, CD103, and CTLA4 and impart a T regulatory cell phenotype. FOXP3 is mutated in X-linked autoimmunity-allergic dysregulation syndrome (XLAAD or IPEX) in humans and in "scurfy" mice. Overexpression of FOXP3 has been shown to lead to a hy |
Immunogen | Human FOXP3 delta2 (exon 2 deleted) peptide conjugated to KLH. |
Other Names | Forkhead box protein P3, Scurfin, JM2, IPEX, Zinc finger protein JM2 |
Gene, Accession # | Gene ID: 50943 |
Catalog # | 694802 |
Price | $265 |
Order / More Info | Human FOXP3 Delta 2 (exon 2 deleted) Antibody from BIOLEGEND |
Product Specific References | n/a |