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Antigenic Specificity | TRAF3 |
Clone | 9D7C15 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-TRAF3. TNFR-associated factor 3, also known as TRAF3, is a member of the TNF receptor associated factor (TRAF) protein family and was originally identified as an adaptor molecule binding to the cytoplasmic tail of CD40. The engagement of CD40 with its ligand recruits the complex, which consists of TRAF3, TRAF2, and c-IAP1/2. This results in the stabilization of NF-κB inducing kinase (NIK). NIK phosphorylates the IKKα complex and subsequently leads to the activation of the RelB/p52 complex. TRAF3 is inv |
Immunogen | Partial TRAF3 recombinant protein (1-200 a.a.) expressed in E. coli. |
Other Names | TNF receptor-associated factor 3, CAP1, CD40 receptor-associated factor 1 (CRAF1), CD40-binding protein (CD40BP), LMP1-associated protein 1 (LAP1), IIAE5 |
Gene, Accession # | Gene ID: 7187 |
Catalog # | 680802 |
Price | $229 |
Order / More Info | TRAF3 Antibody from BIOLEGEND |
Product Specific References | n/a |