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Antigenic Specificity | Human/Mouse/Rat MR1 |
Clone | 8F2.F9 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1, κ |
Format | phycoerythrin (PE) conjugate |
Size | 25 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PE anti-human/mouse/rat MR1. MHC-related protein 1, also known as MR1, is a nonclassical MHC class I molecule highly conserved in mammals, particularly in its α1/α2 domains. MR1 is required for the development and expansion of the mucosal-associated invariant T (MAIT) cells. The transcripts for MR1 are ubiquitously expressed, but its expression on the cell surface seems to be ligand-dependent. MR1 is involved in the presentation of vitamin-derived compounds from bacterial biosynthetic pathways. |
Immunogen | Chimeric mMR1/L molecule (mMR1 [alpha1-alpha2 domain]/Ld [alpha3 cytoplasmic tail]) soluble, recombinant protein secreted by insect cells was used to immunize MR1 KO mice |
Other Names | Major Histocompatibility Complex Class I-related, HLALS |
Gene, Accession # | Gene ID: 3140, 15064, 25119 |
Catalog # | 396105 |
Price | $159 |
Order / More Info | Human/Mouse/Rat MR1 Antibody from BIOLEGEND |
Product Specific References | n/a |