TICAM-1 (TRIF) Antibody from BIOLEGEND
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| Antigenic Specificity | TICAM-1 (TRIF) |
| Clone | 1H4B01 |
| Host Species | Mouse |
| Reactive Species | human, mouse |
| Isotype | IgG2a, κ |
| Format | purified |
| Size | 100 µg |
| Concentration | n/a |
| Applications | Western Blot (WB), ICC, IP, IHC-P |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Purified anti-TICAM-1 (TRIF). TICAM-1, also known as TRIF, is an intracellular adaptor protein utilized by TLR3 and TLR4. TLR3 recognizes double stranded viral RNA and induces TICAM-1 mediated type I interferon production. The N-terminal region of TICAM-1 recruits TBK1 and IKKi, which in turn phosphorylates the interferon regulatory transcription factor IRF3. The phosphorylated IRF3 is subsequently dimerized and translocates to the nucleus, resulting in transcriptional activation of the gene encoding IFN-β. Mice lacking in T |
| Immunogen | Partial human TICAM-1 recombinant protein (29-204 a.a.) |
| Other Names | TIR domain-containing adapter molecule 1, TRIF, MyD88-3, Proline-Rich, Vinculin And TIR Domain-Containing Protein B (PRVTIRB) |
| Gene, Accession # | Gene ID: 148022 |
| Catalog # | 657102 |
| Price | $265 |
| Order / More Info | TICAM-1 (TRIF) Antibody from BIOLEGEND |
| Product Specific References | PubMed: 29403489, 29691463, 33444549 |
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