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Antigenic Specificity | Mouse CD284 (TLR4) |
Clone | SA15-21 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a, κ |
Format | purified |
Size | 25 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC), IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-mouse CD284 (TLR4). Toll-like receptors are highly conserved from Drosophila to humans and share structural and functional similarities. They are type I transmembrane signaling receptors which activate the innate immune system in response to pathogen invasion. So far, at least 13 TLR members have been identified. The secretory protein, MD2, associates with cell-surface bound TLR4 (CD284) on monocytes, B cells, and T cells. TLR4 has been recognized as critical for host recognition of LPS in conjunction with MD2. |
Immunogen | LPS-stimulated TLR4/MD-2/CD14 cotransfected NKR cells. |
Other Names | Toll-like Receptor 4/MD2 complex, TLR4-MD2-complex, TLR4/MD2, CD284/MD2 |
Gene, Accession # | Gene ID: 21898 |
Catalog # | 145401 |
Price | $77 |
Order / More Info | Mouse CD284 (TLR4) Antibody from BIOLEGEND |
Product Specific References | PubMed: 29181004, 31015326, 32438408, 33830504 |