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Antigenic Specificity | Mouse CD369 (Dectin-1, CLEC7A) |
Clone | RH1 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG1, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-mouse CD369 (Dectin-1, CLEC7A). CD369 (Dectin-1), also known as CLEC7A, is a 43 kD type II transmembrane protein. The extracellular portion of Dectin-1 contains one C-type lectin domain, and its cytoplasmic tail has one immunoreceptor tyrosine-based activation motif (ITAM). Dectin-1 binds β-1,3-linked and β-1,6-glucans (abundant in the cell wall of fungi and yeast), mediates phagocytosis, and induces cytokine production and oxidative burst. It is also involved in TLR2-mediated NF-kB activation. Dectin-1 is expressed by macrop |
Immunogen | n/a |
Other Names | BGR, βGR, CD369 |
Gene, Accession # | Gene ID: 56644 |
Catalog # | 144302 |
Price | $218 |
Order / More Info | Mouse CD369 (Dectin-1, CLEC7A) Antibody from BIOLEGEND |
Product Specific References | PubMed: 30606613, 30606613 |