LC3 Antibody from BIOLEGEND
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| Antigenic Specificity | LC3 |
| Clone | A15143K |
| Host Species | Mouse |
| Reactive Species | human, mouse |
| Isotype | IgG2b, κ |
| Format | purified |
| Size | 25 µg |
| Concentration | n/a |
| Applications | IHC-P, ICC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Purified anti-LC3. Microtubule-associated protein light chain 3, commonly known as LC3, is a central protein in the autophagy pathway and functions in autophagosome biogenesis. LC3 is a member of the ATG8 protein family and expressed as three isoforms: LC3A (MAP1LC3A), LC3B (MAP1LC3B), and LC3C (MAP1LC3C). Newly synthesized LC3 is hydrolyzed by the cysteine protease ATG4B to produce the active cytosolic form termed LC3I. Through a series of reactions involving other ATGs, LC3I becomes attached to phosphatidylethan |
| Immunogen | A synthetic peptide corresponding to N-terminal region of human LC3B protein (between amino acid residues 1-50) conjugated to KLH. |
| Other Names | Microtubule-associated proteins 1A/1B light chain 3B, MAP1A/MAP1B LC3 B, MAP1A/1B light chain 3 B, MAP1 light chain 3-like protein 2, autophagy-related ubiquitin-like modifier LC3 B |
| Gene, Accession # | Gene ID: 81631 |
| Catalog # | 848801 |
| Price | $112 |
| Order / More Info | LC3 Antibody from BIOLEGEND |
| Product Specific References | PubMed: 29936182, 29936182, 29936182, 33979611 |
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