Edit |   |
---|---|
Antigenic Specificity | Mouse/Rat TNF-α |
Clone | TN3-19.12 |
Host Species | Armenian Hamster |
Reactive Species | mouse, rat |
Isotype | IgG |
Format | purified |
Size | 50 µg |
Concentration | n/a |
Applications | ELISA Capture, IP, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-mouse/rat TNF-α. TNF-α is secreted by macrophages, monocytes, neutrophils, T-cells, and NK-cells. Many transformed cell lines also secrete TNF-α. Monomeric mouse TNF-α is 156 amino acid protein (N-glycosylated) with a reported molecular weight of 17.5 kD protein. TNF-α forms multimeric complexes; stable trimers are most common in solution. A 26 kD membrane form of TNF-α has also been described. TNF-α binding to surface receptors elicits a wide array of biologic activities including: cytolysis and cytostasis of m |
Immunogen | E. coli-expressed, recombinant mouse TNF-α |
Other Names | Tumor necrosis factor-α, Cachectin, Necrosin, Macrophage cytotoxic factor (MCF), Differentiation inducing factor (DIF), TNFSF-2 |
Gene, Accession # | Gene ID: 21926, 24835 |
Catalog # | 506101 |
Price | $101 |
Order / More Info | Mouse/Rat TNF-α Antibody from BIOLEGEND |
Product Specific References | PubMed: 19693266, 21297009, 32111818, 30878016 |