BTK Phospho (Tyr223) Antibody from BIOLEGEND
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| Antigenic Specificity | BTK Phospho (Tyr223) |
| Clone | A16128B |
| Host Species | Mouse |
| Reactive Species | human, mouse |
| Isotype | IgG2a, κ |
| Format | purified |
| Size | 100 µg |
| Concentration | n/a |
| Applications | Western Blot (WB), Intracellular Staining for Flow Cytometry (ICFC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Purified anti-BTK Phospho (Tyr223). Bruton's tyrosine kinase (BTK) is a Tec family kinase that plays a critical role in B cell development. Upon B cell receptor engagement, BTK translocates to the plasma membrane, where it is transphosphorylated by LYN and SYK kinases at Tyr 551. This initial phosphorylation event is followed by autophosphorylation at Tyr 223. Phosphorylated Tyr 223 is proposed to serve as a docking site for other proteins containing an SH2 domain. Downregulation of BTK activity is achieved through phosphorylation |
| Immunogen | Human BTK peptide phosphorylated at Tyr 223, Complete Freund?s adjuvant. |
| Other Names | Bruton's tyrosine kinase, Bruton agammaglobulinemia tyrosine kinase, AGMX1, ATK, IMD1, PSCTK1, XLA, BPK |
| Gene, Accession # | Gene ID: 695 |
| Catalog # | 601702 |
| Price | $253 |
| Order / More Info | BTK Phospho (Tyr223) Antibody from BIOLEGEND |
| Product Specific References | n/a |
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