TLR4 Antibody from BIORBYT LTD.

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Antigenic SpecificityTLR4
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
FormatATTO-594 conjugate
Size100 ug
Concentration1 mg/ml
ApplicationsFACS, FC, ICC, IHC, WB
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DescriptionRabbit polyclonal to TLR4 (ATTO-594). The Toll-like receptor (TLR) family in mammal comprises a family of trans-membrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and 1L-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules. The TLR family is a phylo-genetically conserved mediator of innate immunity that is essential for microbial recognition. Ten human homologs of TLRs (TLR1-10) have been described. Amount this family of receptors, TLR2 and TLR4 have been most studied. These studies have suggested that TLR2 and TLR4 may serve as potential main mediators of LPS signaling (4,5). The mouse TLR4 cDNA codes for a protein consisting of 839 amino acids, with an approximate molecular weight of 90kDa..
ImmunogenDeveloped against a synthetic peptide corresponding to amino acids 420-435 of human TLR4
Other NamesARMD10, CD284, TLR 4, TOLL, Toll like receptor 4
Gene, Accession #Gene ID: 7099, UniProt: O00206
Catalog #orb152195
Price$526
Order / More InfoTLR4 Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
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Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

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