Glutamine Synthetase / GLUL Antibody from BIORBYT LTD.

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Antigenic SpecificityGlutamine Synthetase / GLUL
CloneGLUL/6601
Host SpeciesMouse
Reactive Speciescanine, human
IsotypeIgG2b, kappa
Formatunconjugated
Size100 ug
Concentrationn/a
ApplicationsIHC-P, WB
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DescriptionGlutamine synthetase (Gl Syn) forms a homo-octamer that serves as a catalyst for the amination of glutamic acid to form glutamine. This enzyme is a marker for astrocytes, which serve as the primary site of conversion of glutamic acid to glutamine in the brain. Induction of glutamine synthetase is seen upon astrocyte cell contact with neurons. Elevated expression of glutamine synthetase in glial cells has been shown to protect neurons from degeneration due to excess glutamate. Glutamine synthetase is also present in the liver and is involved in nitrogen homeostasis. Overexpression of glutamine synthetase has been shown in primary liver cancers, indicating a potential role for glutamine synthetase in hepatocyte transformation.
ImmunogenA recombinant partial protein sequence (within amino acids 50-250) from the human protein was used as the immunogen for the Glutamine Synthetase antibody.
Other Namesn/a
Gene, Accession #UniProt: P15104
Catalog #orb1824337
Price$764
Order / More InfoGlutamine Synthetase / GLUL Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

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