Integrin beta 3 / ITGB3 / CD61 Antibody from BIORBYT LTD.
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|---|---|
| Antigenic Specificity | Integrin beta 3 / ITGB3 / CD61 |
| Clone | ITGB3/2145 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2b, kappa |
| Format | Protein G purified |
| Size | 100 ug, 20 ug |
| Concentration | n/a |
| Applications | IHC-P |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Reacts with human integrin beta3 (GPIIIa, vitronectin receptor beta chain). It associates with the IIb-chain (CD41) to form the GpIIb/GpIIIa complex (CD41/CD61).The CD41/CD61 complex appears early in megakaryocyte maturation. The activated CD41/CD61 complex is a receptor for von Willebrand factor, soluble fibrinogen, fibronectin, vitronectin and thrombospondin. It plays a central role in platelet activation and aggregation. The CD51/CD61 is implicated in tumor metastasis and adenoviral infection. The antibody detects platelets in smears of blood and bone marrow, as well as megakaryocytes in frozen sections and cell smears. The antibody is useful for classification of megakaryoblastic leukemia. |
| Immunogen | A recombinant human partial protein (amino acids 385-490) was used as the immunogen for this ITGB3 antibody. |
| Other Names | n/a |
| Gene, Accession # | UniProt: P05106 |
| Catalog # | orb639752 |
| Price | $764 |
| Order / More Info | Integrin beta 3 / ITGB3 / CD61 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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