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Antigenic Specificity | VGLUT1 |
Clone | S28-9 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | ATTO-390 conjugate |
Size | 100 ug |
Concentration | 1 mg/ml |
Applications | IHC, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse monoclonal to VGlut1 (ATTO-390). VGLUT1 is expressed in a subset of glutamate neurons and transports glutamate into native synaptic vesicles from the brain, exhibiting a conductance for chloride that is blocked by glutamate. Vesicular glutamate transport has a substantially lower apparent affinity than the plasma membrane excitatory amino acid transporters. Glutamate transport by VGLUT1 is saturated with a K(m) of approximately 2 mM, in the same range as transport by synaptic vesicles. Finally, plasma membrane glutamate transporters recognize both aspartate and glutamate as substrates, whereas VGLUT1 does not recognize aspartate.. |
Immunogen | Fusion protein amino acids 493-560 (cytoplasmic C-terminus) of rat VGlut1 |
Other Names | BNPI, SLC17A1, SLC17A1/VGLUT1, Solute Carrier family 17 member 7, Vesicular glutamate transporter 1, VGLUT 1, Brain-specific Na(+)-dependent inorganic phosphate cotransporter |
Gene, Accession # | Gene ID: 116638, UniProt: Q62634 |
Catalog # | orb149715 |
Price | $575 |
Order / More Info | VGLUT1 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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