TOPORS Antibody from BIORBYT LTD.
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|---|---|
| Antigenic Specificity | TOPORS |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 100 ul |
| Concentration | n/a |
| Applications | WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit polyclonal to TOPORS.TOPORS functions as an E3 ubiquitin-protein ligase and an E3 SUMO1-protein ligase. It is a probabletumor suppressor involved in cell growth, cell proliferation and apoptosis. TOPORS regulatesp53/TP53 stability through ubiquitin-dependent degradation. It may regulate chromatin modificationthrough sumoylation of several chromatin modification-associated proteins. It may be involved in DNAdamage-induced cell death through IKBKE sumoylation. Defects in TOPORS are the cause of retinitispigmentosa type 31 P31). |
| Immunogen | C-terminal region of human TOPORS |
| Other Names | TOPORS,E3 ubiquitinprotein ligase Topors,SUMO1protein E3 ligase Topors,Topoisomerase Ibinding RINGfinger protein,Topoisomerase Ibinding arginine,serinerich protein,Tumor suppressor p53bindingprotein 3,p53binding protein 3,p53BP3,LUN |
| Gene, Accession # | UniProt: Q9NS56 |
| Catalog # | orb67252 |
| Price | $527 |
| Order / More Info | TOPORS Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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