TNFSF15 / VEGI / TL1A Antibody from BIORBYT LTD.
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| Antigenic Specificity | TNFSF15 / VEGI / TL1A |
| Clone | VEGI/2052R |
| Host Species | Recombinant Rabbit |
| Reactive Species | human |
| Isotype | IgG, kappa |
| Format | Protein A purified |
| Size | 100 ug, 20 ug |
| Concentration | n/a |
| Applications | IHC-P |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | TNF ligand-related molecule 1 is an anti-angiogenic cytokine that is also called Tumor necrosis factor superfamily, member 15 (TNFSF15) and Vascular endothelial growth inhibitor (VEGI/VEGI192A). This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Reduced expression of TL1A/TNFSF15/VEGI has been reported as a marker of poor prognosis in breast cancer. |
| Immunogen | A full length human recombinant protein was used as the immunogen for this recombinant TNFSF15 antibody. |
| Other Names | n/a |
| Gene, Accession # | Gene ID: 9966, UniProt: O95150 |
| Catalog # | orb606459 |
| Price | $764 |
| Order / More Info | TNFSF15 / VEGI / TL1A Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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