UHRF1 Antibody from BIORBYT LTD.
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| Antigenic Specificity | UHRF1 |
| Clone | 1H9 |
| Host Species | Mouse |
| Reactive Species | human, mouse |
| Isotype | IgG2b |
| Format | unconjugated |
| Size | 100 ul |
| Concentration | 1mg/ml |
| Applications | WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. It is regarded as a hub protein for the integration of epigenetic information. This gene is up-regulated in various cancers, and it is therefore considered to be a therapeutic target. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene exists on chromosome 12. |
| Immunogen | Purified recombinant human UHRF1 protein fragments expressed in E.coil. |
| Other Names | Np95; hNP95; ICBP90; RNF106 |
| Gene, Accession # | Gene ID: 29128, UniProt: Q96T88 |
| Catalog # | orb1732852 |
| Price | $345 |
| Order / More Info | UHRF1 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
BIORBYT LTD.
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Email: info@biorbyt.com
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