Pan Cytokeratin Cocktail (Acidic + Basic) Antibody from BIORBYT LTD.

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Antigenic SpecificityPan Cytokeratin Cocktail (Acidic + Basic)
CloneSPM115 + SPM116
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1, kappa
Formatphycoerythrin (PE) conjugate
Size100 tests
Concentrationn/a
ApplicationsFACS, IF
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DescriptionTwenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which include CK1, CK3, CK4, CK5, CK6, CK8, CK10, CK14, CK15, CK16, and CK19. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. This MAb is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It has been used to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and has shown high sensitivity in the recognition of epithelial cells and carcinomas.
ImmunogenHuman epidermal keratin was used as the immunogen for the Pan Cytokeratin antibody.
Other Namesn/a
Gene, Accession #UniProt: Q7Z794
Catalog #orb1716114
Price$764
Order / More InfoPan Cytokeratin Cocktail (Acidic + Basic) Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
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