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Antigenic Specificity | Fibrillarin |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | IgG |
Format | unconjugated |
Size | 100 ul |
Concentration | 1mg/ml |
Applications | IP, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Fibrillarin is a 2'-O-methyltransferase located in fibrillar regions and Cajal bodies of the nucleolus, where RNA transcription and pre-RNA processing take place. Fibrillarin associates with several other structual proteins as well as box C/D snoRNA to form a complex that functions in pre-rRNA processing, pre-rRNA methylation and ribosome assembly. This complex catalyzes site-specific 2'-O-ribose methylation of targeted nucleotides within the rRNA sequence. The sequence, structure and function of fibrillarin are highly conserved and fibrillarin gene expression is essential for early embryonic development. |
Immunogen | A synthetic peptide of human Fibrillarin |
Other Names | FIB; FLRN; Nop1; RNU3IP1 |
Gene, Accession # | Gene ID: 2091, UniProt: P22087 |
Catalog # | orb1731973 |
Price | $345 |
Order / More Info | Fibrillarin Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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