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Antigenic Specificity | DM-1 |
Clone | monoclonal |
Host Species | n/a |
Reactive Species | mouse |
Isotype | IgG1 | kappa |
Format | biotin conjugate |
Size | 200 ug, 25 ug |
Concentration | n/a |
Applications | n/a |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mertansine (DM-1) is a tubulin inhibitor that binds to the ends of microtubules and inhibits microtubule dynamics. DM-1(Mertansine) has antitumor activity and functions as a regulator of tubulin. It is an alpha-amino acid ester, a carbamate, an epoxide, an organic heterocyclic tetracyclic compound, an organochlorine compound, a mercaptan, and a maydenin alkaloid. DM-1, derived from Mydenin, is a cytotoxic component of antibody-drug conjugations that produce antibody-drug conjugations via a sulfhydryl group splice with SPP (n-succinimide 4- (2-pyridyl dithio)) or SMCC (4- (3-mercapto-2, 5-dioxy-1 pyrrolidyl) -cyclohexanic acid) splice. |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | orb1821772 |
Price | $2053 |
Order / More Info | DM-1 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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