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Antigenic Specificity | IMP3 / Insulin like growth factor 2 mRNA binding protein 3 |
Clone | IMP3/8934R |
Host Species | Recombinant Rabbit |
Reactive Species | human |
Isotype | IgG, kappa |
Format | unconjugated |
Size | 20 ug |
Concentration | n/a |
Applications | IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Imp3, also known as BRMS2, C15orf12 or MRPS4, is a 184 amino acid protein that contains one S4 RNA-binding domain and is the mammalian homolog of the yeast Imp3 protein. Localized to the nucleus, Imp3 exists as a component of a heterotrimeric complex consisting of MPP10, Imp3 and Imp4 and, in this complex, plays a key role in early cleavage events during pre-18S ribosomal processing. The gene encoding Imp3 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes. |
Immunogen | A recombinant fragment of human protein was used as the immunogen for the IMP3 antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: Q9NV31 |
Catalog # | orb1825401 |
Price | $405 |
Order / More Info | IMP3 / Insulin like growth factor 2 mRNA binding protein 3 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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