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Antigenic Specificity | Cystatin A |
Clone | rCSTA/8995 |
Host Species | Recombinant Mouse |
Reactive Species | human |
Isotype | IgG2b, kappa |
Format | unconjugated |
Size | 100 ug |
Concentration | n/a |
Applications | IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer. |
Immunogen | A recombinant fragment of human protein (around aa 1-98) was used as the immunogen for the CSTA antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: P01040 |
Catalog # | orb1823651 |
Price | $764 |
Order / More Info | Cystatin A Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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