CIP4 Antibody from BIORBYT LTD.
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| Antigenic Specificity | CIP4 |
| Clone | monoclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | IgG |
| Format | unconjugated |
| Size | 100 ul |
| Concentration | 1mg/ml |
| Applications | IHC, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling . Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL. |
| Immunogen | A synthetic peptide of human Cip4 |
| Other Names | STP; CIP4; HSTP; STOT; TRIP-10 |
| Gene, Accession # | Gene ID: 9322, UniProt: Q15642 |
| Catalog # | orb1732137 |
| Price | $345 |
| Order / More Info | CIP4 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
BIORBYT LTD.
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