KDM1A Antibody from BIORBYT LTD.
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| Edit | |
|---|---|
| Antigenic Specificity | KDM1A |
| Clone | 2F6 |
| Host Species | Mouse |
| Reactive Species | human, monkey |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 100 ul |
| Concentration | 1mg/ml |
| Applications | ICC, IP, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me. May play a role in the repression of neuronal genes. |
| Immunogen | Purified recombinant human KDM1/LSD1 protein fragments expressed in E.coli. |
| Other Names | KDM1A; AOF2; KDM1; KIAA0601; LSD1; Lysine-specific histone demethylase 1A; BRAF35-HDAC complex protein BHC110; Flavin-containing amine oxidase domain-containing protein 2 |
| Gene, Accession # | Gene ID: 23028, UniProt: O60341 |
| Catalog # | orb1732592 |
| Price | $345 |
| Order / More Info | KDM1A Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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