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Antigenic Specificity | CD27 |
Clone | LPFS2/8316R |
Host Species | Recombinant Rabbit |
Reactive Species | human |
Isotype | IgG, kappa |
Format | unconjugated |
Size | 100 ug |
Concentration | n/a |
Applications | IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes a protein of a disulfide-linked 120kDa dimer, identified as CD27. It is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFkB and SAPK/JNK and induces apoptosis. |
Immunogen | Recombinant human full-length protein was used as the immunogen for the CD27 antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: P26842 |
Catalog # | orb1825879 |
Price | $764 |
Order / More Info | CD27 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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