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Antigenic Specificity | BMI1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 100 ul |
Concentration | n/a |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit polyclonal to BMI1.BMI1 is a component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required tomaintain the transcriptionally repressive state of many genes, including Hox genes, throughoutdevelopment. PcG PRC1 complex acts via chromatin remodeling and modification of histones; itmediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in itsexpressibility. In the PRC1 complex, BMI1 is required to stimulate the E3 ubiquitin-protein ligaseactivity of RNF2/RING2. |
Immunogen | C-terminal region of human BMI1 |
Other Names | BMI1,BMI1,Bmi1,PCGF4,RNF51,Polycomb group RING finger protein 4,RING finger protein 51 |
Gene, Accession # | UniProt: P35226 |
Catalog # | orb66847 |
Price | $527 |
Order / More Info | BMI1 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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