Pan-HLA MHC II (DP/DQ/DR) Antibody from BIORBYT LTD.

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Antigenic SpecificityPan-HLA MHC II (DP/DQ/DR)
CloneHLA-Pan/8311R
Host SpeciesRecombinant Rabbit
Reactive Specieshuman
IsotypeIgG, kappa
Formatunconjugated
Size100 ug
Concentrationn/a
ApplicationsIHC-P
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DescriptionReacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DP, -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an alpha chain (36kDa) and a beta chain (27kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six alpha and ten beta chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response.
ImmunogenPriess cells (a human B cell line) were used as the immunogen for the Pan-HLA-II antibody.
Other Namesn/a
Gene, Accession #UniProt: P01908
Catalog #orb1823200
Price$764
Order / More InfoPan-HLA MHC II (DP/DQ/DR) Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
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