IRF8 Antibody from BIORBYT LTD.
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| Antigenic Specificity | IRF8 |
| Clone | monoclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | IgG |
| Format | unconjugated |
| Size | 100 ul |
| Concentration | 1mg/ml |
| Applications | IHC, IP, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Plays a role as a transcriptional activator or repressor (PubMed:25122610). Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). Plays a negative regulatory role in cells of the immune system. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF8 and activation of genes . |
| Immunogen | Recombinant protein of human IRF8 |
| Other Names | ICSBP; IRF-8; ICSBP1; IMD32A; IMD32B; H-ICSBP |
| Gene, Accession # | Gene ID: 3394, UniProt: Q02556 |
| Catalog # | orb1731787 |
| Price | $345 |
| Order / More Info | IRF8 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
BIORBYT LTD.
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P: +44 (0)1223 859 353
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info@biorbyt.com
http://www.biorbyt.com
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Email: info@biorbyt.com
Phone: +1 (415) 906-5211
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