CD146 / MCAM / MUC18 Antibody from BIORBYT LTD.
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| Antigenic Specificity | CD146 / MCAM / MUC18 |
| Clone | MCAM/3048 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2b, kappa |
| Format | Protein G purified |
| Size | 100 ug, 20 ug |
| Concentration | n/a |
| Applications | IHC-P |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease. |
| Immunogen | A recombinant human partial protein (amino acids 226-374) was used as the immunogen for the MCAM antibody. |
| Other Names | n/a |
| Gene, Accession # | UniProt: P43121 |
| Catalog # | orb639798 |
| Price | $764 |
| Order / More Info | CD146 / MCAM / MUC18 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
BIORBYT LTD.
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