SHANK1/SHANK3 Antibody from BIORBYT LTD.
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| Antigenic Specificity | SHANK1/SHANK3 |
| Clone | S367-51 |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG2a |
| Format | ATTO-488 conjugate |
| Size | 100 ug |
| Concentration | 1 mg/ml |
| Applications | ICC, IHC, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Mouse monoclonal to SHANK1 (ATTO-488). SHANK proteins are scaffolding adaptors that have been shown to integrate neurotransmitter receptors into the cortical cytoskeleton at postsynaptic densities. SHANK1-3 of the SHANK/ProSAP family are molecular scaffolds in the postsynaptic density (PSD). SHANK recruits betaPIX and PAK to dendritic spines to regulate postsynaptic structure and interacts with ionotropic receptor and metabotropic glutamate receptor complexes. Transcript splice variation in the Shank family influences the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain to ensure normal development.. |
| Immunogen | Fusion protein amino acids 538-626 (SH3 domain) of rat SHANK3. Mouse: 100% identity (89/89 amino acids identical). Human: 97% identity (87/89 amino acids identical). ~70% identity with SHANK1 and SHANK2. |
| Other Names | Shank postsynaptic density protein, SH3 and multiple ankyrin repeat domains 3, Proline rich synapse associated protein 2, Proline-rich synapse-associated protein 2, ProSAP2, PSAP2, SH3 and multiple ankyrin repeat domains protein 3, SH3/ankyrin domain gene 3,Shank3b, SPANK 2, SPANK2, KAP/SAPAP interacting protein, OTTHUMP00000174437, SH3 and multiple ankyrin repeat domains 1, SH3 and multiple ankyrin repeat domains protein 1, SH3/ankyrin domain gene 1, SHANK 1, Shank1, Shank1a, Somatostatin receptor interacting protein, Somatostatin receptor-interacting protein, SPANK 1, SPANK1, SSTR interacting protein, SSTR-interacting protein, SSTRIP, Synamon, AI841104, DEL22q13.3, KIAA1650 |
| Gene, Accession # | Gene ID: 59312, UniProt: Q9JLU4 |
| Catalog # | orb150822 |
| Price | $573 |
| Order / More Info | SHANK1/SHANK3 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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