NME2 / Nucleoside diphosphate kinase B / NDKB Antibody from BIORBYT LTD.

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Antigenic SpecificityNME2 / Nucleoside diphosphate kinase B / NDKB
CloneNME2/6434
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2, kappa
Formatunconjugated
Size20 ug
Concentrationn/a
ApplicationsIHC-P, WB
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DescriptionThe nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP). In humans, NDP kinases A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human c-Myc promotor.
ImmunogenRecombinant full-length human protein was used as the immunogen for the Nucleoside diphosphate kinase B antibody.
Other Namesn/a
Gene, Accession #UniProt: P22392
Catalog #orb1825032
Price$405
Order / More InfoNME2 / Nucleoside diphosphate kinase B / NDKB Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
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