ACTN2 / Alpha Actinin 2 / Sarcomeric Alpha Actinin Antibody from BIORBYT LTD.

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Antigenic SpecificityACTN2 / Alpha Actinin 2 / Sarcomeric Alpha Actinin
CloneACTN2/3294
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2b, kappa
FormatProtein G purified
Size20 ug, 100 ug
Concentrationn/a
ApplicationsIHC-P, WB
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DescriptionAlpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In non-muscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.
ImmunogenAmino acids 557-692 from the human protein were used as the immunogen for this ACTN2 antibody.
Other Namesn/a
Gene, Accession #UniProt: P35609
Catalog #orb640016
Price$405
Order / More InfoACTN2 / Alpha Actinin 2 / Sarcomeric Alpha Actinin Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
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