CD40 Antibody from BIORBYT LTD.
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| Edit | |
|---|---|
| Antigenic Specificity | CD40 |
| Clone | FGK45.5 |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2a, kappa |
| Format | Protein G purified |
| Size | 100 ug, 20 ug |
| Concentration | n/a |
| Applications | FACS, Functional Studies, IF |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Upon binding to its ligand CD154, CD40 acts as a costimulatory molecule for the activation of B cells, dendritic cells, monocytes, and other APCs. CD40 plays roles in B cell activation, differentiation, proliferation and Ig isotype switching as well as dendritic cell maturation. FGK4.5 can be used for blocking of CD40/CD154 interaction and forin vitroandin vivoactivation of CD40 expressing APCs. This MAb is shown to indirectly activate natural killer (NK) cells, producing significant antitumor and anti-metastatic effects. Effective in boosting immune responses against infectious agents and can potentially be used to treat chronic autoimmune inflammatory processes. |
| Immunogen | Purified recombinant Mouse CD40 fusion protein was used as the immunogen for the CD40 antibody. |
| Other Names | n/a |
| Gene, Accession # | UniProt: P27512 |
| Catalog # | orb640140 |
| Price | $764 |
| Order / More Info | CD40 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
BIORBYT LTD.
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Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240
info@biorbyt.com
http://www.biorbyt.com
U.S. OFFICE
Biorbyt LLC
1100 Corporate Square Drive
Helix Center, Suite 221
St Louis, MO 63132
Email: info@biorbyt.com
Phone: +1 (415) 906-5211
Fax: +1 (415) 651-8558
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