S100P Antibody from BIORBYT LTD.

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Antigenic SpecificityS100P
CloneS100P/4386R
Host SpeciesRecombinant Rabbit
Reactive Specieshuman
IsotypeIgG
FormatProtein A purified
Size20 ug, 100 ug
Concentrationn/a
ApplicationsIHC-P
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DescriptionS100P is a 95-amino-acid protein and a member of the S100 family. S100P has been shown to mediate tumor growth, metastasis and invasion through the binding of Ca2+ ions, receptor for advanced glycation end products, cytoskeletal protein ezrin, calcyclin-binding protein/Siah-1-interacting protein and cathepsin D.S100P highly expressed in human placenta, gastrointestinal tract, and esophageal mucosa, but always negative in pancreas and liver. Overexpression of S100P has been detected in several cancers such as breast, colon, prostate, pancreatic and lung carcinomas, and the protein has been functionally implicated in carcinogenic processes. S100P could potentially serve as diagnostic marker, prognostic/predictive indicator and therapy target for different carcinomas.
ImmunogenA recombinant fragment corresponding to the C-terminal region of human S100P protein was used as the immunogen for the recombinant S100P antibody.
Other Namesn/a
Gene, Accession #UniProt: P25815
Catalog #orb699804
Price$405
Order / More InfoS100P Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
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Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

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