NKX2.1 / TTF1 Antibody from BIORBYT LTD.

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Antigenic SpecificityNKX2.1 / TTF1
CloneNX2.1/1855R
Host SpeciesRecombinant Rabbit
Reactive Specieshuman, mouse, rat
IsotypeIgG, kappa
FormatProtein A purified
Size20 ug, 100 ug
Concentrationn/a
ApplicationsIHC-P
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DescriptionNKX2.1/TTF-1 is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver, stomach, pancreas, small intestine, colon, kidney, breast, skin, testes, pituitary, prostate, and adrenal glands are unreactive. Anti-NKX2.1 is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast, mediastinal germ cell tumors, and malignant mesothelioma. It can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates. Loss of NKX2.1 expression in non-small cell lung carcinoma has been associated with aggressive behavior of such neoplasms. NKX2.1 reactivity is also seen in thyroid malignancies.
ImmunogenRecombinant protein was used as the immunogen for the recombinant NKX2.1 antibody.
Other Namesn/a
Gene, Accession #UniProt: P43699
Catalog #orb606478
Price$405
Order / More InfoNKX2.1 / TTF1 Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
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