PAX4 Antibody from BIORBYT LTD.

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Antigenic SpecificityPAX4
ClonePAX4/7599
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1, kappa
Formatunconjugated
Size20 ug
Concentrationn/a
ApplicationsIHC-P
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DescriptionPax-4 (paired box gene 4) protein influences normal differentiation of Insulinproducing beta cells and influences normal pancreatic islet development. Pax-4 protein is a transcriptional repressor that binds to a common cis element in the Glucagon, Insulin and Somatostatin promoters. Mouse Pax-4 transcript is present in pancreatic islets, and the islet beta cell lines MIN6, beta TC and NIT1. Differentiation of endoderm-derived endocrine pancreas is mediated through Pax-4 and Pax-6. Pax-4 may act as a Pax-6 repressor due to the competition for binding sites and lower transactivation potential of Pax-4. The human Pax-4 gene encodes a deduced 350 amino acid protein that is 80% identical to the deduced mouse Pax-4 protein.
ImmunogenA recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the Paired box 4 antibody.
Other Namesn/a
Gene, Accession #UniProt: O43316
Catalog #orb1822965
Price$405
Order / More InfoPAX4 Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

info@biorbyt.com

http://www.biorbyt.com

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St Louis, MO 63132
Email: info@biorbyt.com
Phone: +1 (415) 906-5211
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