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Antigenic Specificity | NCOA1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 100 ul |
Concentration | n/a |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit polyclonal to NCOA1.NCOA1 is a nuclear receptor coactivator that directly binds nuclear receptors and stimulates thetranscriptional activities in a hormone-dependent fashion. NCOA1 is involved in the coactivation ofvarious nuclear receptors, such as for steroids (PGR, GR and ER), retinoids XRs), thyroid hormone(TRs) and prostanoids (PPARs). NCOA1 is also involved in coactivation mediated by STAT3,STAT5A, STAT5B and STAT6 transcription factors. NCOA1 displays histone acetyltransferase activitytoward H3 and H4, and plays a central role in creating multisubunit coactivator complexes that act byboth chromatin remodeling and recruient of general transcription factors. |
Immunogen | N-terminal region of human NCOA1 |
Other Names | NCOA1,Nuclear receptor coactivator 1,NCoA1,Class E basic helixloophelix protein 74,bHLHe74,ProteinHin2,RIP160,Renal carcinoma antigen NYREN52,Steroid receptor coactivator 1,SRC1,BHLHE74,SRC1 |
Gene, Accession # | UniProt: Q15788 |
Catalog # | orb66875 |
Price | $527 |
Order / More Info | NCOA1 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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